Arbeitsgemeinschaft für Gen-Diagnostik e.V.

Annual Meeting of the AGD 2023

26./27. October

Topic: Thinking beyond short read genomes


AGD continues with the popular hybrid format: Online and Universitätsclub Bonn, Konviktstraße 9, 53113 Bonn.


October 26. and 27., 2023.


As the highly anticipated Modellvorhaben Genomsequenzierung prepares for its much-awaited launch on January 1, 2024, we are excited to reveal a program that goes beyond short read sequencing in this year's AGD meeting. The agenda will feature interesting talks on long read sequencing, novel DNA methylation assays, and collaborative research empowered by FAIR data principles, fostering a more interconnected and accessible scientific community. Network with colleagues and enjoy the food!

Is there anything to win?

Submit your abstract by October, 1 for a chance to win 30 m₿ (1st prize), 20 m₿ (2nd prize), or 10 m₿ (3rd prize)*. For AGD members, participation in the conference is free of charge - and the annual membership fee is as low as the registration fee. Becoming a member pays off!

(*) 1 m₿ is 0.001 Bitcoin. At the time of writing 1 ₿ is 24,000 €.


Send an email (best with your abstract) to or use the web registration form below.

Preliminary program

Thursday, October 26
11:00–12:00 Screening of Posters in the Auditorium
12:00–12:45 Lunch Break and Opening of the Industrial Exhibition
12:45–13:00 Welcome and Opening of the Scientific Symposium
13:00–15:30 German NGS competence centers (session 1)
Session Chair: Joachim Schultze, DZNE, Germany
13:00–13:30 Rebekka Wehner and Fabian Rost (Dresden-concept Genome Center, Dresden)
Characterizing the immune architecture of melanoma metastases
A spatial multi-omics approach
13:30–14:00 Franziska Kimmig (Competence Centre for Genomic Analysis, Kiel)
Population-based analysis of longitudinal variation in peripheral blood transcriptomes
14:00–14:30 Kerstin Ludwig (West German Genome Center, Bonn)
Sequencing large cohorts provides insights into COVID-19 host genetics
14:30–15:00 Nicolas Casadei (NGS Competence Center Tübingen, Tübingen)
Evolution of sequencing services at the NCCT
15:00-15:30 Alexander Vogel (Oxford Nanopore, German)
Recent advances in long read sequencing with nanopores
15:30–16:00 Coffee Break, Industrial Exhibition and Poster Viewing
16:00–18:00 Long read sequencing (session 2)
Session Chair: Peter Krawitz, University Hospital Bonn
16:00–16:30 Florian Kraft (Aachen, Germany)
LonGER - A German initiative for ONT long read sequencing in diagnostics
16:30–17:00 Stephan Ossowksi (Tübingen, Germany)
Variant detection in complex genomic regions using Nanopore sequencing
17:00–17:30 Helene Kretzmer (Max Planck, Berlin, Germany)
Real-time brain cancer classification with nanopore sequencing
17:30–18:00 Felix Wolter (Pacific Biosciences, USA)
Recent advances and applications of PacBio HiFi sequencing for rare diseases and oncology
18:00–19:00 Rudi Balling (Bonn, Germany)
Is there clinical utility in self-monitoring with omics data?
19:00–20:00 Buffet, Opening Networking Mixer (exhibitors are invited)
20:00–open end Alleles & Allies: Workshops and game night
Friday, October 27
9:00–11:00 Methylation assays in the clinic (session 3)
Session Chair: Ingo Kurth, University Hospital Aachen, Germany
09:00–09:20 Pascal Giehr (LMU, Munich, Germany)
Chasing non-canonical nucleotides using Third-Generation-Sequencing
09:20–09:40 Bekim Sadicovic (Western University, Canada)
Evaluation of DNA Methylation signatures in neurodevelopmental disorders
09:40–10:00 Wolfgang Wagner (Aachen, Germany)
Toward Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis
10:00-10:20 Jochen Seggewiss and Oliver Latz (Twist Bioscience, Germany)
Twist´s flexible methylation detection solution: from 100 to 4.000.000 CpGs
10:20–10:40 Manuel Holtgrewe (Charité, Germany)
SV calling from ONT long-read data: benchmarks, and new approaches
10:40–11:00 Joachim Weischenfeldt (Copenhagen, Denmark)
Leveraging long read sequencing to resolve complex SVs in cancer genomes
11:00–11:30 Coffee Break, Industrial Exhibition and Poster Viewing
11:30–13:30 Joint research in medical genomics (session 4)
Session Chair: Sebahattin Cirak, University Hospital Ulm, Germany
11:30-11:45 Vanessa di Pasco (Nanodigmbio)
μCaler: Small Target – Big Data
11:45-12:00 Oliver Stephan (Element Biosciences)
The Element AVITI™: Democratizing access to highly accurate DNA sequencing
12:00-12:30 Christian Gebhard (MGZ, Germany)
FindMe2care, Kontaktplattform für seltene genetische Erkrankungen
12:30–13:00 Oliver Kohlbacher (Tübingen, Germany)
Perspectives for the further development of the DNPM:dip
13:00–13:30 Annette Grüters-Kieslich (ELHKS, Berlin)
Warum brauchen wir das Modellvorhaben Genomsequenzierung?
13:30–14:15 Oral presentations of poster prize winners 2022 and awards 2023
14:15–16:00 Buffet, Industrial Exhibition
14:45–16:00 AGD General Assembly
16:00 End of Meeting
19:00 Speaker's Dinner im Nees

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